IJERPH, Free Full-Text

Aluminum is an element found in nature and in cosmetic products. It can interfere with the metabolism of other cations, thus inducing gastrointestinal disorder. In cosmetics, aluminum is used in antiperspirants, lipsticks, and toothpastes. The aim of this work is to investigate aluminum bioavailability after accidental oral ingestion derived from the use of a toothpaste containing a greater amount of aluminum hydroxide than advised by the Scientific Committee on Consumer Safety (SCCS). To simulate in vitro toothpaste accidental ingestion, the INFOGEST model was employed, and the amount of aluminum was measured through the ICP-AES analysis. Tissue barrier integrity was analyzed by measuring transepithelial electric resistance, and the tissue architecture was checked through light microscopy. The margin of safety was also calculated. Overall, our results indicate that the acute exposure to aluminum accidentally ingested from toothpastes is safe for the final user, even in amounts higher than SCCS indications.

2024 Significance of 28th february - IJERPH Free Full-Text The

IJERPH, Free Full-Text, one piece 1057 twitter

IJERPH, Free Full-Text

IJERPH, Free Full-Text, time control contabilidade fotos

IJERPH, Free Full-Text

NextGEM project on LinkedIn: NextGEM: Next-Generation Integrated

IJERPH Free Full-Text Challenges In Preventive Practices

Sunrise Sign Language Academy Sign language Courses, Translation

IJERPH Free Full-Text Challenges In Preventive Practices